Asthma and Sinus and Colostrum

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Colostrum for Asthma

and associated sinus problems

Dear consumer,

You inquiry regarding the use of colostrum for individuals suffering fromasthma and sinus problems has been forwarded to me. I am a business andtechnology consultant with extensive knowledge regarding the formation and composition ofbovine colostrum and its medical applications in humans and animals.

Asthma is a disorder of the respiratory system in which the passages that enable air to pass intoand out of the lungs narrow, causing wheezing, coughing and shortness of breath due to arestriction of air intake. More than 17 million Americans suffer from asthma and it occursequally in males and females and in all ethnic and socio-economic groups. The prevalence ofasthma increased more than 60% in Americans between 1982 and 1994. Scientists suspect thatthe sharp increase was due to more exposure to second-hand smoke, growing populations inpolluted city centers and new housing that was poorly ventilated.

Asthma attacks occur when the bronchi and bronchioles become inflamed, usually by contactwith a triggering irritant such as pet hair or cigarette smoke. This reduces the space throughwhich air can travel through the lungs, causing the lungs to work harder to move air in and out.The attack usually begins with mild chest pressure and a dry cough and, as the attack intensifies,wheezing develops and breathing becomes difficult with the cough producing a stringy mucous.Since the airway inflammation prevents some of the oxygen-rich air from reaching the alveoli,the cells of the body start to burn oxygen at a higher rate, which actually increases the body'sdemand for oxygen.

Inflammation of the airway occurs when an irritant comes into contact with the airway walls.The body's immune system detects the irritant as foreign and releases an immunoglobulin of theIgE class that can attach to the irritant. This triggers the release of specialized white blood cells,known as mast cells, that head for the site of irritation. When they get there, the mast cellsrelease histamine, a chemical substance that causes swelling and redness as part of aninflammatory response. This cause the muscles lining the airway to contract even more,narrowing the passage further. The cells that line the airway overreact to the inflammatoryresponse and secrete a lotof mucous, which clogs the bronchioles and causes the wheezing.

The most common causes of asthma attacks are extremely small and lightweight particles thatare transported through the air and inhaled into the lungs. For many people, the environmentaltriggers are allergens like plant pollen, mold spores, animal dander and fecal material from dustmites and cockroaches. The triggers can also be physiological, like exercise and infections suchas the common cold. Alternatively, attacks may be brought on by substances found in food, suchas the sulfites used to preserve beer and wine, and in medications like aspirin and ibuprofen.Your friend's sinus problems are likely linked closely to her asthma. The paranasal sinuses areair-filled, mucous-lined cavities in the head and cheekbones and in the frontal bone just aboveand between the eye sockets. The sinuses all drain into the nasal cavity. The sinuses are ofteninfected with bacteria, causing inflammation and severe pain. Environmental and chemicalirritants, as well as most allergens, can similarly cause a mild to severe inflammatory response inthe sinuses. In all cases, the inflammation results in overproduction of mucous by cells lining thecavities. Repeated attacks often lead to a thickening of the mucous membranes and, sometimes,scarification requiring surgical intervention, which frequently provides only temporary relief.So what can be done about all of this. The answer is routine dietary supplementation with a highquality bovine colostrum and here is why.

First, allergic reactions and asthma are manifestations of an immune system that is out of control.The problem is that at about age 13, the body's health support mechanisms began to deteriorate.Before puberty, when you were just a young child, the very foundation of your immune systemwas being established by a small gland-like structure in the upper chest, the thymus. It is withinthis structure that the cells mature that will determine the appropriate type of response that yourimmune system should mount after an insult and then cells from the same source will regulatethe quality and intensity of that response. Cells from this gland also scan the blood for abnormalcells and remove them. After puberty, the thymus begins to shrink and ultimately almostdisappears by age 50-60. So, although the immune system develops more immunologic memorywith time, it gradually loses the ability to efficiently and effectively orchestrate and direct theactual immune response itself.

When dealing with any type of inflammatory condition, including an infection, it is wise torecognize that the best defense is founded on a good offense. Scientific studies have shown thatinsulin-like growth factor (IGF-1), a major component of high quality bovine colostrum, and theIGF superfamily of proteins can restore and maintain a fully functional thymus, even in adults. Inaddition, colostrum contains the alpha and beta chains of the hormone thymosin that actindependently and in concert to regulate the functions of the thymus. Further, the proline-richpeptide (PRP), also known as thymulin, in colostrum is known to down-regulate the immunesystem and keep the response to a foreign substance under control. Other studies have shownthatincluding only small amounts of colostrum in the daily diet of adult animals significantlyenhances the ability of their white blood cells to respond to infection and destroy invadingbacteria and viruses.

Thus, routine dietary supplementation with a high quality first milking colostrum, like that fromImmune-Tree, will strengthen and support the immune system and help your friend to keep herimmune system operating at an optimum level and hold the inflammatory response in check or,at a minimum, reduce the impact of the asthma attacks. I would suggest that she routinelyconsume5-6 500 mg capsules or the equivalent powder daily and that she attempt to increase this to 8-10capsules daily during the periods when she historically has experienced the most frequent attacks.I hope that the above information gives you a better understanding of your friend's condition andthe benefits that can be realized by routinely supplementing the diet with Immune-Treescolostrum.


Ancell CD, Phipps J, Young L; Thymosin alpha-1, Am J Health Sys Pharm 2001; 58(10): 879-85.Aspinal R, Andrew D, Pido-Lopez J; Age associated changes in thymopoesis, Springer Semin Immunopathol 2002;24(1): 87-101.Clark R, et al; Insulin-like growth factor-1 stimulation of lymphopoesis, J Clin Invest 1993; 92(2): 540-8.Fry TJ, Mackall CL; Current concepts of thymic aging, Springer Semin Immunopathol 2002; 24(1): 7-22.Grimberg A, Cohen P; Role of insulin-like growth factors and their binding proteins in growth control andcarcinogenesis, J Cell Physiol 2000; 183(1): 1-9.Hwa V, Oh Y, Rosenfeld RG; The insulin-like growth factor binding protein IGFBP) superfamily, Endocrin Rev1999; 20(6): 761-87.

To your good health - always.


Alfred E. Fox, Ph.D.

Dr. Alfred E. Fox holds a Ph.D. from Rutgers University in Microbiology (Immunochemistry)and has more than 25 years of senior management experience at Carter-Wallace, Baxter DadeDivision and Warner-Lambert, where he was responsible for research and development andregulatory affairs. He was also the founder and president of two biotechnology companiesfocused on agribusiness and environmental monitoring, respectively. For the past 15 years, Dr.Fox has been the President of Fox Associates, a business and technology consulting firm servingsmall- to mid-size companies in the human and animal healthcare fields. He focuses primarilyon marketing and regulatory issues and for the past 10 years has continuously consulted tobovine colostrum manufacturers, where he has gained regulatory approval for their products,been a technical advisor, helped design and develop marketing strategies and served as anexpert witness in legal matters.

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